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Awesome.

Researchers have developed a new gene editing tool that is more efficient and easier to use. CRISPR-EZ addresses the issue of target RNA accuracy and embryo viability in IVF transgenic mice.

( andrew modzelewski/lin he | university of california berkeley )

CRISPR gene editing has been the subject of many researchers around the world because of its great potential in the study human genetic disease. But more than that, scientists have high regard for this tool because it can help cure complex and debilitating diseases like dementia and cancer.

As more fine-tuning is done in the use of CRISPR gene editing, more diseases can be effectively cured. CRISPR-Cas9 has been used to accurately replace or change genes but it is mostly done in early embryos, and there is a need to increase its accuracy and ease of use. With this in mind, researchers from the University of California (UC) Berkeley have developed a new method called CRISPR-EZ (CRISPR ribonucleoprotein electroporation of zygotes) that would make gene editing easier.

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With 3D printers (like the one in India) printing buildings while leveraging AI technology we could see the building of complexes in space v. needing an inflatable room.

NASA on Saturday successfully expanded and pressurized an add-on room at the International Space Station two days after aborting the first attempt when it ran into problems.

The flexible habitat, known as the Bigelow Expandable Activity Module (BEAM), completed slowly extending 67 inches (170 centimeters) at 4:10 pm (2010 GMT) following more than seven hours during which astronaut Jeff Williams released short blasts of air into the pod’s walls from the orbiting lab using a manual valve.

After the expansion was completed, he opened eight air tanks inside BEAM, pressurizing the pod to a level close to the space station’s 14.7 pounds per square inch.

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When nerve cells have to communicate with each other in our brains, it involves release of neurotransmitters acting as messengers at neural synapses. Here the released neurotransmitter is bound and registered by receptors at the surface of the receiving nerve cell. This will, in turn, trigger a signal which is sent on to other nerve cells. The circuits in the brain using the neurotransmitters noradrenaline, dopamine, GABA and serotonin are known to play an important role in mood, reward and mental well-being, and they also have a key role to in mental disorders such as addiction and depression.

See Also: Obesity is associated with brain’s neurotransmitters

After release of neurotransmitters between nerve cells, they must, however, be removed again to end the signal. This is done by a family of transport proteins which function as molecular vacuum cleaners in the cell membrane of the nerve cell where they pump the neurotransmitter back into the nerve cell for later reuse. This transport is of great importance to the signaling between the nerve cells, but happens relatively slowly. A collaborative project between researchers from Aarhus University has made it possible to explain what happens in the crucial rate-limiting step in the transport process for neurotransmitters such as serotonin, noradrenaline, GABA and dopamine which are all transported by related proteins with the same mechanism.

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Awesome.

The 3D-printed office was constructed using a special mixture of cement and a set of building material designed and made in the UAE and the United States. To ensure reliability, the materials have undergone a range of tests in both China and the United Kingdom.

A 3D-printer measuring 20-feet high, 120-feet long and 40-feet wide was used to print the building that featured an automated robotic arm to implement printing process.

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