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May 2, 2016

The World’s Tiniest Light-Powered Engines Could Revolutionize Medicine

Posted by in categories: biotech/medical, neuroscience

Nanomachines could revolutionize technology and modern medicine, if only we had viable power sources to make them move where we wanted them to go. Now scientists at the University of Cambridge have built the world’s tiniest engines, powered by light, as described in a new paper in the Proceedings of the National Academy of Sciences.

Dubbed “ANTs” (for actuating nano transducers), these itsy-bitsy devices could one day realize the vision of the 1966 classic film Fantastic Voyage, in which a miniaturized submarine crew travel through the body of an injured scientist to repair a blood clot in his brain—except there would be no need for shrunken human pilots. Like real ants, these nano engines can produce very large forces relative to their weight, according to lead researcher Jeremy Baumberg.

It works a bit like a spring mechanism. At the heart of the device are lots of charged gold nanoparticles, held together by a polymer gel that responds to changes in temperature. The gel is heated by zapping it with a laser. The polymer gel responds by expelling all its water in a fraction of a second and collapsing, much like coiling a spring. This stores elastic energy as the gold nanoparticles are smushed together into tight clusters.

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May 2, 2016

Watch the Smallest Nuclear Explosion With Bobby Kennedy

Posted by in category: military

Yeah, nuclear mortar. GREAT idea, that. lol wink


The Davy Crockett nuclear weapon was carried by a jeep and operated by a three-man crew.

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May 2, 2016

Spider Bot 3D Printers

Posted by in categories: 3D printing, robotics/AI

These aren’t spiders—they’re 3D printers that can walk.

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May 2, 2016

That time a bot invaded Thingiverse and created weird new 3D objects

Posted by in categories: cybercrime/malcode, robotics/AI

I guess this falls into those code bugs in AI that Google’s Vint Cerf has stated his own larger concer around AI.


Some called it art, some called it spam—and some thought it might be a new life form.

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May 2, 2016

Adult brain prunes branched connections of new neurons

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

When tweaking its architecture, the adult brain works like a sculptor—starting with more than it needs so it can carve away the excess to achieve the perfect design. That’s the conclusion of a new study that tracked developing cells in an adult mouse brain in real time.

New began with a period of overgrowth, sending out a plethora of neuronal branches, before the brain pruned back the connections. The observation, described May 2, 2016 in Nature Neuroscience, suggests that new cells in the have more in common with those in the embryonic brain than scientists previously thought and could have implications for understanding diseases including autism, intellectual disabilities and schizophrenia.

“We were surprised by the extent of the pruning we saw,” says senior author Rusty Gage, a professor in Salk’s Laboratory of Genetics and holder of the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease.

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May 2, 2016

Cognitive-behavioral therapy may help reduce memory problems in cancer survivors who have received chemotherapy

Posted by in categories: biotech/medical, neuroscience

A new analysis indicates that a type of psychotherapy delivered by videoconference may help prevent some of the long-term memory issues caused by chemotherapy. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings point to a noninvasive way to help cancer survivors manage some of the negative effects of their treatment.

It’s estimated that approximately half of cancer patients who receive chemotherapy develop long-lasting changes in memory function such as trouble remembering conversational content or steps in a task. While the memory problems tend to be mild, they diminish quality of life in areas of job performance and family and social life well beyond cancer treatment. The causes of this problem and reasons why it does not affect every survivor remain unknown, and there is currently limited research on treatments for it.

A team led by Robert Ferguson, PhD, who is currently at the University of Pittsburgh Cancer Institute but was at the Eastern Maine Medical Center and Lafayette Family Cancer Center in Bangor, Maine, while conducting this research, developed a cognitive-behavioral therapy called “Memory and Attention Adaptation Training” (MAAT), which helps cancer survivors to increase awareness of situations where memory problems can arise and to develop skills to either prevent memory failure or to compensate for memory dysfunction.

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May 2, 2016

FDA new sheriff in town in Silicon Valley

Posted by in categories: biotech/medical, health

Silicon Valley’s newest valley member; wonder if Google or eBay will send a “Welcome Basket” to the FDA?


Helmy Eltoukhy’s company is on a roll. The start-up is a leading contender in the crowded field of firms working on “liquid biopsy” tests that aim to be able to tell in a single blood draw whether a person has cancer.

Venture investors are backing Guardant Health to the tune of nearly $200 million. Leading medical centers are testing its technology. And earlier this month, it presented promising data on how well its screening tool, which works by scanning for tiny DNA fragments shed by dying tumor cells, worked on an initial group of 10,000 patients with late-stage cancers.

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May 2, 2016

US military proposes secure, self-destructing messaging app

Posted by in categories: military, neuroscience

Military’s new Mission Impossible style messaging.


The U.S. military needs new messaging technology that’s ultra-secure and self-destructs. Sound familiar?

Think SnapChat. That’s an important part of what the Defense Advanced Research Projects Agency (DARPA) is aiming to do via a request for proposals posted on a DOD Web page. In Phase III of the project, DARPA says it requires “a secure messaging system that can provide… one time eyes only messages,” among a host of other features. Similarly, SnapChat allows a message to be viewed for a short length of time (1 to 10 seconds) before it becomes inaccessible, the primary reason it has become such a popular messaging platform.

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May 2, 2016

Scientists May Have Discovered a New Particle That Could Completely Change Physics as We Know It

Posted by in categories: innovation, particle physics

New particle found can re-write Physics.


It could be nothing at all. Or it could be a breakthrough.

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May 2, 2016

10 responses to “Hacking Aging”

Posted by in categories: biotech/medical, law, life extension, mathematics

What would you say if I told you that aging happens not because of accumulation of stresses, but rather because of the intrinsic properties of the gene network of the organism? I’m guessing you’d be like: surprised .

So, here’s the deal. My biohacker friends led by Peter Fedichev and Sergey Filonov in collaboration with my old friend and the longevity record holder Robert Shmookler Reis published a very cool paper. They proposed a way to quantitatively describe the two types of aging – negligible senescence and normal aging. We all know that some animals just don’t care about time passing by. Their mortality doesn’t increase with age. Such negligibly senescent species include the notorious naked mole rat and a bunch of other critters like certain turtles and clams to name a few. So the paper explains what it is exactly that makes these animals age so slowly – it’s the stability of their gene networks.

What does network stability mean then? Well, it’s actually pretty straightforward – if the DNA repair mechanisms are very efficient and the connectivity of the network is low enough, then this network is stable. So, normally aging species, such as ourselves, have unstable networks. This is a major bummer by all means. But! There is a way to overcome this problem, according to the proposed math model.

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