Suppose you’re trying to solve a puzzle that includes both words and pictures — like reading a comic strip and figuring out what happens next. That’s the kind of challenge today’s AI faces in “multimodal reasoning,” where it must understand both text and images to think and respond accurately.

A new study reveals how CRISPR gene editing could potentially eradicate Down syndrome.

An experimental LLM from OpenAI solved some of the world’s hardest math problems at the 2025 International Math Olympiad, the company said.

Gravity is normal on Earth, but out there it plays a deeper role. If a cosmic body is massive enough, it could bend the spacetime and cause distortions.

Scientists discovered that ancient viral DNA sequences called MER11, once dismissed as genetic junk, actually act as important gene switches.

In a new study, Nobel laureate David Baker and colleagues detail new methods for targeting undruggable “disordered” proteins.

To understand how the molecular machinery of synapses works, it is essential to determine an inventory of synaptic proteins at a subsynaptic resolution. Nevertheless, synaptic proteins are difficult to localize because of the low expression levels and limited access to immunostaining epitopes. Here, we report on the exTEM (epitope-exposed by expansion-transmission electron microscopy) method that enables the imaging of synaptic proteins in situ. This method combines TEM with nanoscale resolution and expandable tissue-hydrogel hybrids for enhanced immunolabeling with better epitope accessibility via molecular decrowding, allowing successful probing of the distribution of various synapse-organizing proteins. We propose that exTEM can be employed for studying the mechanisms underlying the regulation of synaptic architecture and function by providing nanoscale molecular distribution of synaptic proteins in situ. We also envision that exTEM is widely applicable for investigating protein nanostructures located in densely packed environments by immunostaining of commercially available antibodies at nanometer resolution.

End-of-life nonhuman primates can be used to screen pools of lipid nanoparticles for clinical safety studies.

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Scientists need to learn how information flows to congressional staffers—and the crucial role they play in setting policy.