FUTURISTIC MOVIE TIMELINE

Super proud to announce the first in-depth analysis by our “Rejuvenation Now” initiative: a “Risk-Benefit Analysis of.

An in-depth analysis — more than 200 pre-clinical and clinical trials.

Scientists have created an image which zooms in to a tiny section inside a cell. This is not a simulation, it is the real thing. As you run the video, you will see the section highlighted in green and then thin yellow tubes inside it. These are strands of the body’s clotting agent ready to be transported to the site of a wound.

But observers warn that there are several factors that could stymie the nation’s plans, including a lack of contribution to the theories used to develop the tools underpinning the field, and a reticence by Chinese companies to invest in the research needed to make fundamental breakthroughs.

The country’s artificial-intelligence research is growing in quality, but the field still plays catch up to the United States in terms of high-impact papers, people and ethics.

Mexico-based startup Biomitech has developed an artificial tree that it claims is capable of sucking up the equivalent amount of air pollution as 368 living trees. In doing so, it could be a game-changer for polluted cities lacking enough free space to plant a forest of real trees.

The Universe is expanding, and that expansion is speeding up over time. These two facts have been well established through observation, but we don’t know what’s causing that expansion. It seems to be some mysterious, unknown energy that acts like the opposite of gravity.

We call this hypothetical energy “dark energy”, and it’s been calculated to constitute around 72 percent of all the stuff that makes up the Universe. We don’t know what it actually is. But a new experiment has just allowed us to rule out one more thing that it isn’t: a new force.

“This experiment, connecting atomic physics and cosmology, has allowed us to rule out a wide class of models that have been proposed to explain the nature of dark energy, and will enable us to constrain many more dark energy models,’‘said physicist Ed Copeland of the University of Nottingham.

NASA just successfully demonstrated the first of three tools designed to refuel spacecraft in space, right outside of the International Space Station.

The space agency’s Robotic Refuelling Mission 3 was able to unstow a special adapter that can hold super-cold methane, oxygen or hydrogen, and insert it into a special coupler on a different fuel tank.

Future iterations of the system could one day allow us to gas up spacecraft with resources from distant worlds, such as liquid methane as fuel. And that’s a big deal, since future space explorations to far away destinations such as the Moon and Mars will rely on our ability to refuel after leaving Earth’s gravity.

Physics World represents a key part of IOP Publishing’s mission to communicate world-class research and innovation to the widest possible audience. The website forms part of the Physics World portfolio, a collection of online, digital and print information services for the global scientific community.

Physicists have found “electron pairing,” a hallmark feature of superconductivity, at temperatures and energies well above the critical threshold where superconductivity happens.

Rice University’s Doug Natelson, co-corresponding author of a paper about the work in this week’s Nature, said the discovery of Cooper pairs of electrons “a bit above the critical temperature won’t be ‘crazy surprising’ to some people. The thing that’s more weird is that it looks like there are two different energy scales. There’s a higher energy scale where the pairs form, and there’s a lower energy scale where they all decide to join hands and act collectively and coherently, the behavior that actually brings about superconductivity.”

Electrical resistance is so common in the modern world that most of us take it for granted that computers, smartphones and electrical appliances warm up during use. That heating happens because electricity doesn’t flow freely through the metal wires and silicon chips inside the devices. Instead, flowing electrons occasionally bump into atoms or one another, and each collision produces a tiny bit of heat.

A research team led by the University of California San Diego has discovered the root cause of why lithium metal batteries fail—bits of lithium metal deposits break off from the surface of the anode during discharging and are trapped as “dead” or inactive lithium that the battery can no longer access.

The discovery, published Aug. 21 in Nature, challenges the conventional belief that lithium metal batteries fail because of the growth of a layer, called the solid electrolyte interphase (SEI), between the lithium anode and the electrolyte. The researchers made their discovery by developing a technique to measure the amounts of inactive lithium species on the anode—a first in the field of battery research—and studying their micro- and nanostructures.

The findings could pave the way for bringing rechargeable lithium metal batteries from the lab to the market.

The ability to securely transmit information over the internet is extremely important, but most of the time, eavesdroppers can still generally determine who the sender and receiver are. In some highly confidential situations, it is important that the sender’s and receiver’s identities remain anonymous.

Over the past couple of decades, researchers have been developing protocols for anonymously transmitting messages over classical networks, but similar protocols for quantum networks are still in much earlier stages of development. The anonymity methods that have been proposed for quantum networks so far face challenges such as implementation difficulties or require that strong assumptions be made about the resources, making them impractical for use in the real world.

In a new paper, Anupama Unnikrishnan, Ian MacFarlane, Richard Yi, Eleni Diamanti, Damian Markham, and Iordanis Kerenidis, from the University of Oxford, MIT, Sorbonne University, the University of Paris and CNRS, have proposed the first practical protocol for anonymous communication in quantum networks.

Self-assembled materials are attractive for next-generation materials, but their potential to assemble at the nanoscale and form nanostructures (cylinders, lamellae etc.) remains challenging. In a recent report, Xundu Feng and colleagues at the interdisciplinary departments of chemical and environmental engineering, biomolecular engineering, chemistry and the center for advanced low-dimension materials in the U.S., France, Japan and China, proposed and demonstrated a new approach to prevent the existing challenges. In the study, they explored size-selective transport in the water-continuous medium of a nanostructured polymer template formed using a self-assembled lyotropic H₁ (hexagonal cylindrical shaped) mesophase (a state of matter between liquid and solid). They optimized the mesophase composition to facilitate high-fidelity retention of the H₁ structure on photoinduced crosslinking.

The resulting nanostructured polymer material was mechanically robust with internally and externally crosslinked nanofibrils surrounded by a continuous aqueous medium. The research team fabricated a membrane with size selectivity at the 1 to 2 nm length scale and water permeabilities of ~10 liters m⁻² hour⁻¹ bar⁻¹ μm. The membranes displayed excellent anti-microbial properties for practical use. The results are now published on Science Advances and represent a breakthrough for the potential use of self-assembled membrane-based nanofiltration in practical applications of water purification.

Membrane separation for filtration is widely used in diverse technical applications, including seawater desalination, gas separation, food processing, fuel cells and the emerging fields of sustainable power generation and distillation. During nanofiltration, dissolved or suspended solutes ranging from 1 to 10 nm in size can be removed. New nanofiltration membranes are of particular interest for low-cost treatment of wastewaters to remove organic contaminants including pesticides and metabolites of pharmaceutical drugs. State-of-the-art membranes presently suffer from a trade-off between permeability and selectivity where increased permeability can result in decreased selectivity and vice-versa. Since the trade-off originated from the intrinsic structural limits of conventional membranes, materials scientists have incorporated self-assembled materials as an attractive solution to realize highly selective separation without compromising permeability.

(BICA for AI, Post Conference Journal Paper, see Springer)

Abstract:

This paper is focused on preliminary cognitive and consciousness test results from using an Independent Core Observer Model Cognitive Architecture (ICOM) in a Mediated Artificial Super Intelligence (mASI) System. These results, including objective and subjective analyses, are designed to determine if further research is warranted along these lines. The comparative analysis includes comparisons to humans and human groups as measured for direct comparison. The overall study includes a mediation client application optimization in helping perform tests, AI context-based input (building context tree or graph data models), intelligence comparative testing (such as an IQ test), and other tests (i.e. Turing, Qualia, and Porter method tests) designed to look for early signs of consciousness or the lack thereof in the mASI system. Together, they are designed to determine whether this modified version of ICOM is a) in fact, a form of AGI and/or ASI, b) conscious, and c) at least sufficiently interesting that further research is called for. This study is not conclusive but offers evidence to justify further research along these lines.

Any future colonization efforts directed at the Mars all share one problem in common; their reliance on a non-existent magnetic field. Mars’ magnetosphere went dark about 4 billion years ago when it’s core solidified due to its inability to retain heat because of its small mass. We now know that Mars was quite Earth-like in its history. Deep oceans once filled the now arid Martian valleys and a thick atmosphere once retained gasses which may have allowed for the development of simple life. This was all shielded by Mars’ prehistoric magnetic field.

When Mars’ magnetic line of defense fell, much of its atmosphere was ripped away into space, its oceans froze deep into the red regolith, and any chance for life to thrive there was suffocated. The reduction of greenhouse gasses caused Mars’ temperature to plummet, freezing any remaining atmosphere to the poles. Today, Mars is all but dead. Without a magnetic field, a lethal array of charged particles from the Sun bombards Mars’ surface every day threatening the potential of hosting electronic systems as well as biological life. The lack of a magnetic field also makes it impossible for Mars to retain an atmosphere or an ozone layer, which are detrimental in filtering out UV and high energy light. This would seem to make the basic principles behind terraforming the planet completely obsolete.

I’ve read a lot of articles about the potential of supplying Mars with an artificial magnetic field. By placing a satellite equipped with technology to produce a powerful magnetic field at Mars L1 (a far orbit around Mars where gravity from the Sun balances gravity from Mars, so that the satellite always remains between Mars and the Sun), we could encompass Mars in the resulting magnetic sheath. However, even though the idea is well understood and written about, I couldn’t find a solid mathematical proof of the concept to study for actual feasibility. So I made one!

An international team of researchers with partial support from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) developed a new MRI technique that can capture an image of a brain thinking by measuring changes in tissue stiffness. The results show that brain function can be tracked on a time scale of 100 milliseconds – 60 times faster than previous methods. The technique could shed new light on altered neuronal activity in brain diseases.

The human brain responds almost immediately to stimuli, but non-invasive imaging techniques haven’t been able to keep pace with the brain. Currently, several non-invasive brain imaging methods measure brain function, but they all have limitations. Most commonly, clinicians and researchers use functional magnetic resonance imaging (fMRI) to measure brain activity via fluctuations in blood oxygen levels. However, a lot of vital brain activity information is lost using fMRI because blood oxygen levels take about six seconds to respond to a stimulus.

Since the mid-1990s, researchers have been able to generate maps of tissue stiffness using an MRI scanner, with a non-invasive technique called magnetic resonance elastography (MRE). Tissue stiffness can’t be measured directly, so instead researchers use MRE to measure the speed at which mechanical vibrations travel through tissue. Vibrations move faster through stiffer tissues, while vibrations travel through softer tissue more slowly; therefore, tissue stiffness can be determined. MRE is most commonly used to detect the hardening of liver tissue but has more recently been applied to other tissues like the brain.

Astronomers have announced a discovery which may have an essential effect on life on the planet Earth. Another planetary system, which is comprised of planets with the size of our planet, which could probably have water on them and in that way, life too.

Nowadays, scientists that work using telescopes at NASA and the European Southern Observatory announced their astonishing discovery – a whole system of planets with the size of the planet Earth. Well, if this is not enough, this team also claims that the planets’ density measurements indicate that six of them, which are more central, are rocky worlds like our planet.

However, that is only the beginning. Keep reading.

Stellarators, twisty machines that house fusion reactions, rely on complex magnetic coils that are challenging to design and build. Now, a physicist at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL) has developed a mathematical technique to help simplify the design of the coils, making stellarators a potentially more cost-effective facility for producing fusion energy.

“Our main result is that we came up with a new method of identifying the irregular magnetic fields produced by stellarator coils,” said physicist Caoxiang Zhu, lead author of a paper reporting the results in Nuclear Fusion. “This technique can let you know in advance which coil shapes and placements could harm the plasma’s magnetic confinement, promising a shorter construction time and reduced costs.”

Fusion, the power that drives the sun and stars, is the fusing of light elements in the form of plasma—the hot, charged state of matter composed of free electrons and atomic nuclei—that generates massive amounts of energy. Twisty, cruller-shaped stellarators are an alternative to doughnut-shaped tokamaks that are more commonly used by scientists seeking to replicate fusion on Earth for a virtually inexhaustible supply of power to generate electricity.

Tweaked RR params original posted by — [link].

Magnetic resonance imaging is nothing new, but scientists were able to perform an MRI on a single atom. But how?
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Scientists recently captured the smallest MRI ever while scanning an individual atom. The technique successfully reached a breakthrough level of resolution in the world of microscopy, the detailed MRI can reveal single atoms as well as different types of atoms based on their magnetic interactions.

This breakthrough has potential applications in all kinds of fields, like quantum computing where it could be used to design atomic-scale methods of storing info or when it comes to drug development, the ability to control individual atoms could potentially be used to study how proteins fold and then lead to the development of drugs for diseases like Alzheimers.

In a sense, the researchers combined a version of an MRI machine with a special instrument called a scanning tunneling microscope, which turned out to be a match made in microscopy heaven.

An MRI scanner creates an extremely strong magnetic field around whatever it’s trying to image, temporarily re-aligning the protons in your body with that magnetic field. Then the MRI machine pulses the sample (or patient) with a radiofrequency, which pulls the protons slightly out of alignment with the magnetic field. And after the brief radiofrequency pulse is over, the protons snap back into alignment with the field, and the energy that’s released as the protons move back into place with the magnetic field is what is detected and visualized by the machine.

And a scanning tunneling microscope is used for imaging really tiny surfaces, and it can pick up certain properties like size and molecular structure.

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Circa 2017

We have reported a new phenomenon in acute wound healing following the use of intracellular ATP delivery—extremely rapid tissue regeneration, which starts less than 24 h after surgery, and is accompanied by massive macrophage trafficking, in situ proliferation, and direct collagen production. This unusual process bypasses the formation of the traditional provisional extracellular matrix and significantly shortens the wound healing process. Although macrophages/monocytes are known to play a critical role in the initiation and progression of wound healing, their in situ proliferation and direct collagen production in wound healing have never been reported previously. We have explored these two very specific pathways during wound healing, while excluding confounding factors in the in vivo environment by analyzing wound samples and performing in vitro studies. The use of immunohistochemical studies enabled the detection of in situ macrophage proliferation in ATP-vesicle treated wounds. Primary human macrophages and Raw 264.7 cells were used for an in vitro study involving treatment with ATP vesicles, free Mg-ATP alone, lipid vesicles alone, Regranex, or culture medium. Collagen type 1α 1, MCP-1, IL-6, and IL-10 levels were determined by ELISA of the culture supernatant. The intracellular collagen type 1α1 localization was determined with immunocytochemistry. ATP-vesicle treated wounds showed high immunoreactivity towards BrdU and PCNA antigens, indicating in situ proliferation. Most of the cultured macrophages treated with ATP-vesicles maintained their classic phenotype and expressed high levels of collagen type 1α1 for a longer duration than was observed with cells treated with Regranex. These studies provide the first clear evidence of in situ macrophage proliferation and direct collagen production during wound healing. These findings provide part of the explanation for the extremely rapid tissue regeneration, and this treatment may hold promise for acute and chronic wound care.

Wound healing is a complex and dynamic process involving the replacement of devitalized and missing structures. The traditional view of wound healing is that it involves hemostasis, inflammation, proliferation, and remodeling, and these steps result in a lag of 3–6 d before reepithelialization starts [1,2]. We have discovered that the intracellular delivery of adenosine triphosphate using ATP-vesicles as an acute wound treatment enhances wound healing [3,4]. The most unprecedented finding was that new tissue started to generate within 24 h, and it continued to grow to eliminate the wound cavity quickly [4–6]. This growth was attained by early and massive monocyte/macrophage trafficking, proliferation, and fast collagen production for direct formation of extracellular matrix (ECM).

GONE ARE the days when conspiracy-mongers had to find shards of evidence and contort it to convince people. Now, just their malevolence is needed. If a concocted scenario can’t be proved, then perhaps it can’t be disproved either. That is toxic for a stable society and politics. So how did we get here, and how do we get out?

Nancy L. Rosenblum of Harvard University and Russell Muirhead of Dartmouth College are the authors of “A Lot of People Are Saying: The New Conspiracism and the Assault on Democracy” (Princeton, 2019). Though conspiracy theories have always existed, they note that today something is different and dangerous: “Conspiracy without the theory.”

We need to have higher ethics for robotic beings because if the superintelligence in digital form becomes reality we will need to have better ethics around robot rights. We could have literally a terminator situation but we could make a the vision possibly we do not need to have them be slaves to use but rightful citizens.

Each notice cited the same section of these guidelines, which states: “Content that displays the deliberate infliction of animal suffering or the forcing of animals to fight is not allowed on YouTube.”

It goes on to state: “Examples include, but are not limited to, dog fighting and cock fighting.”

Cambridge Quantum Computing has a demo of its quantum key security generation at Ironbridgeapi.com.

A provocative new study is suggesting a blood test tracking 14 different biomarkers can predict a person’s risk of dying within the next 10 years better than any conventional models. The research is still a long way off being broadly deployed in clinical environments and the test may be of most use in human drug trials as a surrogate endpoint for mortality.

© 2019 EPFL / Alain Herzog. OpticSELINE electrode array for intraneural stimulation of the optic nerve, developed in the Translational Neural Engineering Lab, and used in preliminary studies.

Vast interstellar events where clouds of charged matter hurtle into each other and spew out high-energy particles have now been reproduced in the lab with high fidelity. The work, by MIT researchers and an international team of colleagues, should help resolve longstanding disputes over exactly what takes place in these gigantic shocks.

Many of the largest-scale events, such as the expanding bubble of matter hurtling outward from a supernova, involve a phenomenon called collisionless shock. In these interactions, the clouds of gas or plasma are so rarefied that most of the particles involved actually miss each other, but they nevertheless interact electromagnetically or in other ways to produces visible shock waves and filaments. These high-energy events have so far been difficult to reproduce under laboratory conditions that mirror those in an astrophysical setting, leading to disagreements among physicists as to the mechanisms at work in these astrophysical phenomena.

Now, the researchers have succeeded in reproducing critical conditions of these collisionless shocks in the laboratory, allowing for detailed study of the processes taking place within these giant cosmic smashups. The new findings are described in the journal Physical Review Letters, in a paper by MIT Plasma Science and Fusion Center Senior Research Scientist Chikang Li, five others at MIT, and 14 others around the world.

WASHINGTON — Several hundred million ash trees around the nation have fallen victim to a beetle known as the emerald ash borer. Thousands of doomed trees once stood tall in the D.C. area, according to bug guy Mike Raupp, an entomologist at the University of Maryland.

“This is a devastating pest,” said Raupp.

Local governments are fighting back against what Raupp says is a tsunami of the beetles, which chew their way into the tree and feed on what’s underneath the bark.

Researchers at the University of Sfax, in Tunisia, have recently developed a new method to recognize handwritten characters and symbols in online scripts. Their technique, presented in a paper pre-published on arXiv, has already achieved remarkable performance on texts written in both the Latin and Arabic alphabet.

In recent years, researchers have created neural network-based architectures that can tackle a variety of tasks, including image classification, face recognition, natural language processing (NLP), and many more. Handwriting recognition systems are computer tools that are specifically designed to recognize characters and other hand-written symbols in a similar way to humans.

In their early years of life, in fact, human beings innately develop the ability to understand different types of handwriting by identifying specific characters both individually and when grouped together. Over the past decade or so, many studies have tried to replicate this ability in computer systems, as this would ultimately enable more advanced and automatic analyses of handwritten texts.

Theoretical physicists at Trinity College Dublin are among an international collaboration that has built the world’s smallest engine—which, as a single calcium ion, is approximately ten billion times smaller than a car engine.

Work performed by Professor John Goold’s QuSys group in Trinity’s School of Physics describes the science behind this tiny motor. The research, published today in international journal Physical Review Letters, explains how random fluctuations affect the operation of microscopic machines. In the future, such devices could be incorporated into other technologies in order to recycle waste heat and thus improve energy efficiency.

The engine itself—a single calcium ion—is electrically charged, which makes it easy to trap using electric fields. The working substance of the engine is the ion’s “intrinsic spin” (its angular momentum). This spin is used to convert heat absorbed from laser beams into oscillations, or vibrations, of the trapped ion.

A group of researchers led by Skoltech Professor Pavel Troshin studied coordination polymers, a class of compounds with scarcely explored applications in metal-ion batteries, and demonstrated their possible future use in energy storage devices with a high charging/discharging rate and stability. The results of their study were published in the journal Chemistry of Materials.

The charging/discharging rate is one of the key characteristics of lithium-ion batteries. Most modern commercial batteries need at least an hour to get fully charged, which certainly limits the scope of their application, in particular, for electric vehicles. The trouble with active materials, such as the most popular anode material, graphite, is that their capacity decays significantly, as their charging rate increases. To retain the battery capacity at high charging rates, the active electrode materials must have high electronic and ionic conductivity, which is the case with the newly-discovered coordination polymers that are derived from aromatic amines and salts of transition metals, such as nickel or copper. Although these compounds hold a great promise, their application in lithium-ion batteries remains virtually unexplored.

A recent study undertaken by a group of scientists from Skoltech and the Institute for Problems of Chemical Physics of RAS led by Professor P. Troshin in collaboration with the University of Cologne (Germany) and the Ural Federal University, focused on tetraaminobenzene-based linear polymers of nickel and copper. Although the linear polymers exhibited much lower initial electronic conductivity as compared to their two-dimensional counterparts, it transpired that they can be used as anode materials that get charged/discharged in less than a minute, because their conductivity increases dramatically after the first discharge due to lithium doping.

Researchers have developed artificial ‘chameleon skin’ that changes color when exposed to light and could be used in applications such as active camouflage and large-scale dynamic displays.

The material, developed by researchers from the University of Cambridge, is made of tiny particles of gold coated in a polymer shell, and then squeezed into microdroplets of water in oil. When exposed to heat or light, the particles stick together, changing the color of the material. The results are reported in the journal Advanced Optical Materials.

In nature, animals such as chameleons and cuttlefish are able to change color thanks to chromatophores: skin cells with contractile fibers that move pigments around. The pigments are spread out to show their color, or squeezed together to make the cell clear.

This could lead to self-healing cars.

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a mathematical framework that can turn any sheet of material into any prescribed shape, inspired by the paper craft termed kirigami (from the Japanese, kiri, meaning to cut and kami, meaning paper).

Unlike its better-known cousin origami, which uses folds to shape paper, kirigami relies on a pattern of cuts in a flat paper sheet to change its flexibility and allow it to morph into 3D shapes. Artists have long used this artform to create everything from pop-up cards to castles and dragons.

“We asked if it is possible to uncover the basic mathematical principles underlying kirigami and use them to create algorithms that would allow us to design the number, size and orientation of the cuts in a flat sheet so that it can morph into any given shape,” said L. Mahadevan, de Valpine Professor of Applied Mathematics, Physics, and Organismic and Evolutionary Biology, the senior author on the paper.

Nearly one year ago to the day, we first revealed Curtiss Motorcycle’s upcoming Zeus V8 electric motorcycle. And now we’re learning that the innovative electric motorcycle has already begun production, thanks to a recently announced partnership.

He solved a 127-year-old physics problem on paper and proved that off-centered boat wakes could exist. Five years later, practical experiments proved him right.

“Seeing the pictures appear on the computer screen was the best day at work I’ve ever had,” says Simen Ådnøy Ellingsen, an associate professor at NTNU’s Department of Energy and Process Engineering.

That was the day that Ph.D. candidate Benjamin Keeler Smeltzer and master’s student Eirik Æsøy had shown in the lab that Ellingsen was right and sent him the photos from the experiment. Five years ago, Ellingsen had challenged accepted knowledge from 1887, armed with a pen and paper, and won.

Scientists have identified a specific gene they believe could be a key player in the changes in brain structure seen in several psychiatric conditions, such as schizophrenia and autism.

The team from Cardiff University’s Neuroscience and Mental Health Research Institute has found that the deletion of the gene CYFIP1 leads to thinning of the insulation that covers nerve cells and is vital for the smooth and rapid communications between different parts of the brain.

The new findings, published in the journal Nature Communications and highlighted in the journal Nature Reviews Neuroscience, throws new light on the potential cause of psychiatric conditions and could ultimately point to new and more effective therapies.

Cold storage for agricultural biodiversity.

Y.-H. Luo et al. Quantum teleportation in high dimensions. Physical Review Letters. Vol. 123, August 16, 2019. doi:10.1103/PhysRevLett.123.070505.

North Korea has miniaturised nuclear warheads and made them small enough to fit on ballistic missiles, Japan believes.

Tokyo defence chiefs warn in a new white paper that North Korea’s military activities pose a ‘serious and imminent threat’.

In last year’s report Japan said it was ‘possible’ that North Korea had achieved miniaturisation, but Tokyo now appears to have upgraded its assessment, according to Japanese newspaper Yomiuri.

SpaceX CEO Elon Musk not only wants to explore Mars, he wants to ‘nuke’ it.

In a tweet this week, Musk reiterated calls to ‘Nuke Mars!’ adding that t-shirts are ‘coming soon.’

Jarring though the idea may be, the tweet is a re-hash of an idea championed by Musk in the past that proposes using a nuclear weapon to terraform the red planet for human habitation.

Carbon can be arranged in a number of configurations. When each of its atoms is bonded to three other carbon atoms, it’s relatively soft graphite. Add just one more bond and it becomes one of the hardest minerals known, diamond. Chuck 60 carbon atoms together in a soccerball shape and boom, buckyballs.

But a ring of carbon atoms, where each atom is bonded to just two others, and nothing else? That’s eluded scientists for 50 years. Their best attempts have resulted in a gaseous carbon ring that quickly dissipated.

So it’s a pretty big deal that a team of researchers, from Oxford University and IBM Research, has now created a stable carbon ring.

The Killers, the short film about cryonics shot by Russian director Vlad Kozlov, who works in the USA, won a Best Director prize at the 37th Flickers: Rhode Island International Film Festival (RIIFF).

RIIFF is one of the most important international film festivals supporting independent filmmakers. The festival has been held annually since 1982 during the second week of August and lasts six days. Its main goal is to discover new talents of independent cinema. More than 5,426 independent films selected from more than 68,000 received applications were presented to the public during the time of existence of the festival. In 2019, 321 films from 51 countries were presented at the festival, which was held from August 6 to August 11 in Rhode Island, USA.

Cryonics as the central element of the plot was shown in a film of this level for the first time. The main roles in the film are played by world-famous actors such as Sherilyn Fenn (Twin Peaks) and Franco Nero (Django). The role of Max, the main character, was played by a young and promising American actor Jeff DuJardin, who had previously worked with Vlad Kozlov on the set of Silent Life, the film about the star of silent film Rudolf Valentino. The producers of the film are Vlad Kozlov, Natalia Dar, Yury Ponomarev, Dmitry Pristankov and David Roberson.

Hot Chips 31 is underway this week, with presentations from a number of companies. Intel has decided to use the highly technical conference to discuss a variety of products, including major sessions focused on the company’s AI division. AI and machine learning are viewed as critical areas for the future of computing, and while Intel has tackled these fields with features like DL Boost on Xeon, it’s also building dedicated accelerators for the market.

The NNP-I 1000 (Spring Hill) and the NNP-T (Spring Crest) are intended for two different markets, inference and training. “Training” is the work of creating and teaching a neural network how to process data in the first place. Inference refers to the task of actually running the now-trained neural network model. It requires far more computational horsepower to train a neural network than it does to apply the results of that training to real-world categorization or classification tasks.

Intel’s Spring Crest NNP-T is designed to scale out to an unprecedented degree, with a balance between tensor processing capability, on-package HBM, networking capability, and on-die SRAMs to boost processing performance. The underlying chip is built by TSMC — yes, TSMC — on 16nm, with a 680mm die size and a 1200mm interposer. The entire assembly is 27 billion transistors with 4x8GB stacks of HBM2-2400 memory, 24 Tensor Processing Clusters (TPCs) with a core frequency of up to 1.1GHz. Sixty-four lanes of SerDes HSIO provides 3.58Tbps of aggregate bandwidth and the card supports an x16 PCIe 4.0 connection. Power consumption is expected to be between 150-250W. The chip was built using TSMC’s advanced CoWoS packaging (Chip-on-Wafer-on-Substrate), and carries 60MB of cache distributed across its various cores. CoWoS competes with Intel’s EMIB, but Intel has decided to build this hardware at TSMC rather than using its own foundries. Performance is estimated at up to 119 TOPS.

Today, we want to spotlight a recent study showing that boosting nicotinamide adenine dinucleotide (NAD+) levels in mice prevents age-related hearing loss.

What is β-Lapachone?

β-Lapachone is a quinone-containing compound that was originally isolated from the lapacho tree in South America. It is worth noting that this tree has been used as a herbal medicine for a number of South and Central American indigenous peoples and that the bark of the tree is sometimes used for making a herbal tea called taheebo.

The semi-annual slow-slip event means dozens of tremors under Puget Sound — and a slightly higher risk of a Cascadia megaquake.

At first, the rough patch on the roof of Mike’s mouth didn’t seem like anything to worry about. It didn’t hurt. But it didn’t go away. His dentist referred him to an ear, nose, and throat doctor, who did a biopsy, which was inconclusive.

In the same decade when gravitational waves and a neutron star merger have been observed, astronomers have now observed what they believe to be the first detection of a black hole swallowing a neutron star.

Last Wednesday, gravitational wave detectors in Italy and the US, called LIGO and Virgo, detected telltale ripples in space and time, traced to an event that happened 8,550 million trillion kilometers away from Earth.

Astronomers are analyzing the data from the detection to confirm the size of the two objects that came together to form such cataclysmic ripples, but the event is likely a black hole eating a neutron star.

High in the Himalayas of India, amid the snow-capped peaks, nestles a mystery. Roopkund Lake is a shallow body of water filled with human bones — the skeletons of hundreds of individuals. It’s these that give the lake its other name, Skeleton Lake, and no one knows how the remains came to be there.

One hypothesis is that some catastrophe, a single event such as a powerful storm, had befallen a large group of people. But DNA analysis of 38 of the skeletons has turned that idea on its head.

The remains appear to come from distinct groups of people from as far as the Mediterranean, and they arrived at the lake several times over a 1,000-year span.

If you don’t want your email provider, its partners, or even hackers skimming your messages, choose one of these providers, which offer end-to-end encryption and other measures.

[Photo: courtesy of Tutanota].

As delicious as butter is—adding flavor and texture to almost any food—it’s not the healthiest thing to smear on toast or corn on the cob. Oil-based spreads like margarine are often considered a better heart-smart alternative, but food scientists at Cornell University have come up with what could be the ultimate butter substitute made primarily from water.

Researchers hope mobile devices can capture signs of imminent risk that a doctor’s questionnaire can’t.

BERKELEY, Calif., Aug. 20, 2019 /PRNewswire/ — Today, the U.S. Patent and Trademark Office has awarded a new patent (U.S. 10,385,360) to the University of California (UC), University of Vienna, and Dr. Emmanuelle Charpentier covering nucleic acid molecules encoding single-molecule guide RNAs, as well as CRISPR-Cas9 compositions comprising single-molecule guide RNAs or nucleic acid molecules encoding single-molecule guide RNAs.

Over the past six months, UC’s U.S. CRISPR-Cas9 portfolio has sharply increased, and to date includes 11 separate patents for methods and compositions related to the gene-editing technology. Looking ahead, UC anticipates at least six additional related patents issuing in the near future, bringing UC’s total portfolio to 17 patents and spanning various compositions and methods including targeting and editing genes in any setting, such as within plant, animal, and human cells. The portfolio also includes patents related to the modulation of transcription.

“The USPTO has continually acknowledged the Doudna-Charpentier team’s groundbreaking work,” said Eldora L. Ellison, Ph.D., lead patent strategist on CRISPR-Cas9 matters for UC and a Director at Sterne, Kessler, Goldstein & Fox. “True to UC’s mission as a leading public university, the patent granted today and others in its CRISPR-Cas9 portfolio will be applied for the betterment of society.”

This is your movement, and your Party, of which I am only the steward. This kind of growth and flourishing of creativity are exactly what I need to see as milestones in the evolution of our participatory mechanisms.

Shareena Z Hamzah does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Cranmer is a member of ATLAS, one of the two general-purpose experiments that, among other things, co-discovered the Higgs boson at the Large Hadron Collider at CERN. He and other CERN researchers recently published a letter in Nature Physics titled “Open is not enough,” which shares lessons learned about providing open data in high-energy physics. The CERN Open Data Portal, which facilitates public access of datasets from CERN experiments, now contains more than two petabytes of information.

It could be said that astronomy, one of the oldest sciences, was one of the first fields to have open data. The open records of Chinese astronomers from 1054 A.D. allowed astronomer Carlo Otto Lampland to identify the Crab Nebula as the remnant of a supernova in 1921. In 1705 Edward Halley used the previous observations of Johannes Kepler and Petrus Apianus—who did their work before Halley was old enough to use a telescope—to deduce the orbit of his eponymous comet.

In science, making data open means making available, free of charge, the observations or other information collected in a scientific study for the purpose of allowing other researchers to examine it for themselves, either to verify it or to conduct new analyses.

Scientists continue to use open data to make new discoveries today. In 2010, a team of scientists led by Professor Doug Finkbeiner at Harvard University found vast gamma-ray bubbles above and below the Milky Way. The accomplishment was compared to the discovery of a new continent on Earth. The scientists didn’t find the bubbles by making their own observations; they did it by analyzing publicly available data from the Fermi Gamma Ray Telescope.

There are lots of smart gadgets that track running, but few track swimming — that is, if you’d like something that’s built for swimming first, as opposed to a device with swim-tracking features tacked on. Form, a new fitness company founded by former Recon Instruments employees, is looking to solve this problem with its first product, the $199 Swim Goggles.

After 10 years in remission, Derek Ruff’s cancer returned, this time as stage IV colon cancer. Despite aggressive rounds of chemotherapy, palliative radiotherapy and immunotherapy, his disease progressed. In February 2019, as part of a phase I clinical trial at Moores Cancer Center at UC San Diego Health, Ruff became the first patient in the world to be treated for cancer with a human-induced pluripotent stem cell (iPSC)-derived cell therapy called FT500.

Moores Cancer Center at UC San Diego Health treats the first patient treated for cancer with a human-induced pluripotent stem cell (iPSC)-derived cell therapy called FT500. Dan Kaufman collaborated with Fate Therapeutics to bring the iPSC-derived natural killer cell cancer immunotherapy to patients.

Tokyo, Aug. 1 (Jiji Press)—Tokyo-based startup A.L.I. Technologies Inc. plans to start accepting reservations for its “hover bike” flying motorcycle from October, company officials said Thursday.

The startup company, which mainly develops small unmanned aerial vehicles, will unveil the product at the Tokyo Motor Show in autumn.

It aims to sell the product mainly to wealthy foreigners, by touting its cutting-edge technologies.

The leaves of a variety of medicinal plants can stop the growth of breast, cervical, colon, leukemia, liver, ovarian, and uterine cancer, a new study shows.

Researchers found the effects in leaves of the bandicoot berry (Leea indica), South African leaf (Vernonia amygdalina), and simpleleaf chastetree (Vitex trifolia). Three other medicinal plants also demonstrated anti-cancer properties.

“Medicinal plants have been used for the treatment of diverse ailments since ancient times, but their anti-cancer properties have not been well studied,” says Koh Hwee Ling, associate professor from the National University of Singapore’s pharmacy department.

Circa 2017

Efficient intracellular delivery of biologically active macromolecules has been a challenging but important process for manipulating live cells for research and therapeutic purposes. There have been limited transfection techniques that can deliver multiple types of active molecules simultaneously into single-cells as well as different types of molecules into physically connected individual neighboring cells separately with high precision and low cytotoxicity. Here, a high frequency ultrasound-based remote intracellular delivery technique capable of delivery of multiple DNA plasmids, messenger RNAs, and recombinant proteins is developed to allow high spatiotemporal visualization and analysis of gene and protein expressions as well as single-cell gene editing using clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein-9 nuclease (Cas9), a method called acoustic-transfection. Acoustic-transfection has advantages over typical sonoporation because acoustic-transfection utilizing ultra-high frequency ultrasound over 150 MHz can directly deliver gene and proteins into cytoplasm without microbubbles, which enables controlled and local intracellular delivery to acoustic-transfection technique. Acoustic-transfection was further demonstrated to deliver CRISPR-Cas9 systems to successfully modify and reprogram the genome of single live cells, providing the evidence of the acoustic-transfection technique for precise genome editing using CRISPR-Cas9.

Intense effusive activity from numerous vents at Stromboli volcano in Italy has resumed again on August 18, 2019, after several days decreased activity.

Frequent and often strong strombolian eruptions occur from several active vents in the crater terrace. Lava from the southwest rim seems to have increased its activity and feeds a lava flow that reaches about halfway down the slope of the Sciara del Fuoco, Dr. Tom Pfeiffer of the Volcano Discovery reported August 18.

Bitcoin offered the first smart contract programming language the world had ever seen. Script, as this language is called, lets users encode different conditions under which coins can be spent. But while this was a revolutionary concept, it’s not easy to use, especially for more complex spending conditions. Both writing a complex contract as well as verifying that the contract does what it is supposed to do are prone to human error. Yet, especially with money at stake, correct interpretation of the conditions is of the utmost importance.

Over the past year, three blockchain engineers have set out to improve this. By stripping down Script to its bare essentials, their “new” programming language — “Miniscript” — abstracts away the complexity and should make programming on Bitcoin easier and safer for everyone involved.

“Miniscript is, in a theoretical sense, more limiting than script,” Blockstream director of research and Miniscript co-designer Andrew Poelstra told Bitcoin Magazine. “But it can do everything that people actually use script for.”

Half a century after the first moon landing, NASA plans to go back to…

Bees, butterflies, and other insects are under attack by the very plants they feed on as U.S. agriculture continues to use chemicals known to kill.

An experiment in the United Kingdom has failed to find evidence of a particle meant to explain most of the universe’s mass. But the search isn’t over.

When cosmologists observe the way the universe expands, they find that present-day theories of matter can’t explain most of the universe’s energy. They call the unknown energy “dark energy,” and theorists have tried to explain it by proposing undiscovered particles and corresponding fields. Experiments have failed to find evidence of such particles, but in physics, that’s not necessarily a bad thing.

From computer hacking to biohacking, Dave Asprey has embarked on a quest to reverse the aging process.

In the 2015 movie “Chappie”, which is set in the near future, automated robots comprise a mechanised police force. An encounter between two rival criminal gangs severely damages the law enforcing robot (Agent 22). His creator Deon recommends dismantling and recycling the damaged police droids. However, criminals kidnap Deon and force him to upload human consciousness into the damaged robot to train it to rob banks. Chappie becomes the first robot with the human mind who can think and feel like a human. Later, in the movie when his creator Deon is dying, it’s Chappie’s turn to upload Deon’s consciousness into a spare robot through a neural helmet. Similarly, in the “Avatar” a 2009 Hollywood science fiction, a character in the film by name Grace connects with Eiwa, the collective consciousness of the planet and transfers her mind to her Avatar body, while another character Jake transfers his mind to his Avatar body rendering his human body lifeless.

Mind uploading is a process by which we relocate the mind, an assemblage of memories, personality, and attributes of a specific individual, from its original biological brain to an artificial computational substrate. Mind uploading is a central conceptual feature of many science fiction novels and films. For instance, Hanson’s book titled “The Age of Em: Work, Love and Life when Robots Rule the Earth” is a 2016 nonfiction book which explores the implications of a future world when researchers have learned to copy humans onto computers, creating “ems,” or emulated people, who quickly come to outnumber the real ones.

We (TIRIAS Research) recently had an opportunity to evaluate the latest Jetson platform from Nvidia. At just 45mm x 70mm the Jetson Nano is the smallest Artificial Intelligence (AI) platform form factor Nvidia has produced to date. The Jetson Nano is powered by the Tegra X1 SoC, which features quad 1.43 GHz Cortex-A57 CPU cores and the 128-core Maxwell GPU. The Jetson Nano also uses the same Jetpack Software Development Kit (SDK) as the other Jetson platforms, the TX2 and AGX Xavier, allowing for cross platform development. For only $99, plus a little extra for accessories, the Jetson Nano is an amazing platform.

In addition to the Tegra X1 SoC, the Nano developer kit comes configured with 4GB of LPDDR4 memory and plenty on I/O options, including a MIPI CSI connector, four USB 3.0 Type-A ports, one USB 2.0 Micro-B, one gigabit ethernet port, and 40 GPIO pins. The Nano is capable of driving dual displays through single DisplayPort and HDMI ports, it has an microSD card slot for storage, and a somewhat hidden M.2 Key E connection for expansion modules/daughter cards for optional functions like wireless connectivity. The Jetson Nano developer kit comes with a sizable heatsink for passive cooling, but has holes drilled for add-on fans. For our evaluation, we used a Noctua NF-A4x20 5V PWM fan and a Raspberry Pi MIPI Camera Module v2 from RS Components and Allied Electronics.

For development software, the Nano runs an Ubuntu Linux OS and uses the Jetpack SDK, which supports Nvidia’s CUDA developer environment, as well as other common AI frameworks, such as TensorRT, VisionWorks, and OpenCV.

Machines on display at World Robot Conference in China can fly, swim and even do brain surgery…

‘It was mesmerizing to watch her stop’: Four-year-old girl with a rare disease is captivated by a beauty advertisement featuring a model in a wheelchair — just like her own.

UK company raises $100m to find fountain of ‘eternal youth’ by cheating death and REVERSING ageing with new technology…

The firm announced a total investment of $10 million from its founders and a further $10 million each from core investors.

Scientists from the International Atomic Energy Agency (IAEA) in Vienna, Austria, released footage of the effect at work in a research reactor…

Experts from the International Atomic Energy Agency in Vienna, Austria, released footage of the effect — a visual equivalent to the ‘sonic boom’ — at work.

A team of scientists from Ohio University, Argonne National Laboratory, Universitié de Toulouse in France and Nara Institute of Science and Technology in Japan led by Ohio Professor of Physics Saw-Wai Hla and Prof. Gwenael Rapenne from Toulouse developed a molecular propeller that enables unidirectional rotations on a material surface when energized.

In nature, molecule propellers are vital in many biological applications ranging from the swimming bacteria to intracellular transport, but synthetic molecular propellers, like what has been developed, are able to operate in harsher environments and under a precise control. This new development is a multiple component molecular propeller specially designed to operate on solid surfaces. This tiny propeller is composed of three components; a ratchet shape molecular gear as a base, a tri-blade propeller, and a ruthenium atom acting as an atomic ball bearing that connects the two. The size of the propeller is only about 2 nanometers (nm) wide and 1 nm tall.

“What is special about our propeller is its multi-component design that becomes chiral on the gold crystal surface, i.e. it forms right- or left-tilted gears,” said Hla. “This chirality dictates the rotational direction when energized.”

It seems that billionaire biotech investor Jim Mellon is the flavor of the month as he continues the drive to create a rejuvenation biotech industry. Jim and his colleagues at Juvenescence have announced that they have secured another $100M for the company, and it will be used to invest and support the growth of promising biotech companies working in this field.

Juvenescence has a varied investment portfolio of companies that range in potential usefulness, depending on your point of view, and they mostly favor the more traditional small molecule drug approach. There are a few companies that are of particular interest.

Modern machine learning applications need to process a humongous amount of data and generate multiple features. Python’s datatable module was created to address this issue. It is a toolkit for performing big data (up to 100GB) operations on a single-node machine, at the maximum possible speed.

By his late 20s, Moe had attained the young adult dream. A technology job paid for his studio apartment just blocks from the beach in Santa Barbara, California. Leisure time was crowded with close friends and hobbies, such as playing the guitar. He had even earned his pilot’s license. “There was nothing I could have complained about,” he says.

Yet Moe soon began a slide he couldn’t control. Insomnia struck, along with panic attacks. As the mild depression he’d experienced since childhood deepened, Moe’s life collapsed. He lost his job, abandoned his interests, and withdrew from his friends. “I lost the emotions that made me feel human,” Moe says. (He asked that this story not use his full name.)

Although many people with depression respond well to treatment, Moe wasn’t one of them. Now 37, he has tried antidepressant drugs and cycled through years of therapy. Moe has never attempted suicide, but he falls into a high-risk group: Though most people with depression don’t die by suicide, about 30% of those who don’t respond to multiple antidepressant drugs or therapy make at least one attempt. Moe was desperate for relief and fearful for his future. So when he heard about a clinical trial testing a new approach to treating depression at Stanford University in Palo Alto, California, near his home, he signed up.

Now, the company is trying yet another approach, launching a new program that lets homeowners rent Tesla solar panels for as little as $50 per month plus tax.

To rent Tesla’s solar panels, you must own a home in Arizona, California, Connecticut, Massachusetts, New Jersey, or New Mexico and be a customer of one of 20 listed utility companies.

The rental rate varies by state and size of the system — small, medium, or large — but in all instances, the single monthly fee is all-encompassing, covering everything from the hardware and installation to maintenance and support.

• Fraud detection techniques mostly stem from the anomaly detection branch of data science.
• If the dataset has sufficient number of fraud examples, supervised machine learning algorithms for classification like random forest, logistic regression can be used for fraud detection.
• If the dataset has no fraud examples, we can use either the outlier detection approach using isolation forest technique or anomaly detection using the neural autoencoder.
• After the machine learning model has been trained, it’s evaluated on the test set using metrics such as sensitivity and specificity, or Cohen’s Kappa.

With global credit card fraud loss on the rise, it is important for banks, as well as e-commerce companies, to be able to detect fraudulent transactions (before they are completed).

According to the Nilson Report, a publication covering the card and mobile payment industry, global card fraud losses amounted to $22.8 billion in 2016, an increase of 4.4% over 2015. This confirms the importance of the early detection of fraud in credit card transactions.

Several companies, like SignAll and Kintrans, have created hand-tracking software that tries, with little success so far, to allow the millions of people that use sign language and an app to easily communicate with anyone.

Now, a new hand-tracking algorithm from Google’s AI labs might be a big step in making this ambitious software everything it originally promised.

RELATED: THIS SMARTPHONE APP CAN SAVE YOUR LIFE WITH JUST 3 WORDS

With more electric cars on the road and the negative environmental impact of traditional vehicle emissions on the forefront of many minds, some may struggle with their choice to drive a car with a standard combustion engine.

But what if you could just “convert” your car into an electric one?

French startup Transition-One says it can do it for only $9,500 — in fact, in France, you also get a subsidy for a converted car so it actually only works out to around $5,600.

Read more

Ranging in size from the experimental Mini Bee , a 250kg technology demonstration spacecraft, through the Honey Bee, capable of capturing a 10m asteroid and extracting its resources, to the Queen Bee, capable of capturing a 40m asteroid for resource extraction. All use an asteroid containment system similar to that proposed for the original Asteroid Redirect Mission, optical mining for resource extraction, and a water based Omnivore Thruster system for propulsion. A variant called the Worker Bee, can serve as an orbital transfer vehicle, transporting items to high Earth orbits and beyond, potentially even to Mars.

Some call it “strong” AI, others “real” AI, “true” AI or artificial “general” intelligence (AGI)… whatever the term (and important nuances), there are few questions of greater importance than whether we are collectively in the process of developing generalized AI that can truly think like a human — possibly even at a superhuman intelligence level, with unpredictable, uncontrollable consequences.

This has been a recurring theme of science fiction for many decades, but given the dramatic progress of AI over the last few years, the debate has been flaring anew with particular intensity, with an increasingly vocal stream of media and conversations warning us that AGI (of the nefarious kind) is coming, and much sooner than we’d think. Latest example: the new documentary Do you trust this computer?, which streamed last weekend for free courtesy of Elon Musk, and features a number of respected AI experts from both academia and industry. The documentary paints an alarming picture of artificial intelligence, a “new life form” on planet earth that is about to “wrap its tentacles” around us.

NEW DELHI (AP) — An unmanned spacecraft India launched last month began orbiting the moon Tuesday as it approaches the lunar south pole to study previously discovered water deposits.

The Indian Space Research Organization said it successfully maneuvered Chandrayaan-2, the Sanskrit word for “moon craft,” into lunar orbit, nearly a month after it left Earth. The mission is led by two female scientists.

Chandrayaan will continue circling the moon in a tighter orbit until reaching a distance of about 100 kilometers (62 miles) from the moon’s surface.

If there’s life on the red planet, our best hope of finding it may be this rock-hungry rover, currently in its final stages of construction (really!) at NASA’s Jet Propulsion Laboratory in Pasadena, California. Next summer, the Mars 2020 rover will be deployed to the Jezero Crater, where it will land in 2021 and spend more than a year prowling the planet’s surface.

The world’s largest all-electric ferry completed its first voyage with passengers last week in Denmark.

The Ellen sailed between the southern Danish ports of Fynshav to Soby, on the island of Aero.

The e-ferry is capable of carrying 30 vehicles and 200 passengers and is powered by a battery “with an unprecedented capacity” of 4.3MWh, according to Swiss battery maker Lechanché which provided the system.

The chip could improve how quickly artificial intelligence systems can…

3D printer manufacturer Electronic Alchemy has developed a system capable of additive manufacturing fully functional electronics. Named eForge, NASA intends to use the system during planetary space missions to 3D print chemical sensors on demand. Following the launch of eForge, the company is also now designing a device to recycle 3D printed electronics, further reducing NASA’s need for resupply missions.

UK biotech valued at $500m and aiming for IPO next year.

Robotic Refueling Mission 3’s Multi-Function Tool 2, operated by Dextre, demonstrates robotic refueling operations on the outside of space station (Credit: NASA)

► Second Lagonda concept ► All-electric, All-Terrain ► Revealed in full at Geneva

After kickstarting the Lagonda brand with the slick Vision Concept at the 2018 Geneva motor show, Aston Martin has returned to the 2019 Geneva motor show with an evolution of this idea called the All-Terrain Concept.

As you can probably guess from the name this new concept stands taller than last year’s Vision Concept, but retains the broad design strokes of its lower, svelte sibling. Not to mention its all-electric drivetrain.

Neurotoxic anticancer drugs, such as platinum-based anticancer drugs, taxanes, vinca alkaloids, and proteasome/angiogenesis inhibitors are responsible for chemotherapy-induced peripheral neuropathy (CIPN). The health consequences of CIPN remain worrying as it is associated with several comorbidities and affects a specific population of patients already impacted by cancer, a strong driver for declines in older adults. The purpose of this review is to present a comprehensive overview of the long-term effects of CIPN in cancer patients and survivors. Pathophysiological mechanisms and risk factors are also presented. Neurotoxic mechanisms leading to CIPNs are not yet fully understood but involve neuronopathy and/or axonopathy, mainly associated with DNA damage, oxidative stress, mitochondria toxicity, and ion channel remodeling in the neurons of the peripheral nervous system. Classical symptoms of CIPNs are peripheral neuropathy with a “stocking and glove” distribution characterized by sensory loss, paresthesia, dysesthesia and numbness, sometimes associated with neuropathic pain in the most serious cases. Several risk factors can promote CIPN as a function of the anticancer drug considered, such as cumulative dose, treatment duration, history of neuropathy, combination of therapies and genetic polymorphisms. CIPNs are frequent in cancer patients with an overall incidence of approximately 38% (possibly up to 90% of patients treated with oxaliplatin). Finally, the long-term reversibility of these CIPNs remain questionable, notably in the case of platinum-based anticancer drugs and taxanes, for which CIPN may last several years after the end of anticancer chemotherapies. These long-term effects are associated with comorbidities such as depression, insomnia, falls and decreases of health-related quality of life in cancer patients and survivors. However, it is noteworthy that these long-term effects remain poorly studied, and only limited data are available such as in the case of bortezomib and thalidomide-induced peripheral neuropathy.

Platinum-based anticancer drugs (i.e., cisplatin, oxaliplatin), proteasome/angiogenesis inhibitors (bortezomib/thalidomide), vinca alkaloids (i.e., vincristine, vinorelbine) and taxanes (i.e., paclitaxel, docetaxel) are the most common anticancer drugs used as first-line chemotherapy for several cancers, including colorectal, gastric, breast and lung cancers, and multiple myeloma. Despite their different action mechanisms, all these anticancer drugs share a common adverse and disabling effect for patients, namely CIPN (Balayssac et al., 2011). CIPN has a considerable impact on cancer treatments and their related symptoms severely affect patients’ daily activities and quality of life. Thus CIPN is often the main adverse effect leading to the reduction or discontinuation of chemotherapy.

Watch Ray Kurzweil’s talk at this years Singularity Summit live!! Go to http://SU.org/live for all the details. #SUSummit #RayKurzweil #Talk #Live

Register below to save your spot.

Solidia’s systems offer superior products that address the cement industry’s goal of reducing its carbon emissions, which contribute 3 to 5% of global CO₂ pollution. Solidia’s patented processes start with an energy-saving, sustainable cement. Concrete made with this cement is then cured with CO₂ instead of water. Together, the sustainable cement and CO2-cured concrete reduce the carbon footprint of cement and concrete by up to 70%. Additionally, up to 100% of the water used in concrete production can be recovered and recycled.

The U.S. Patent and Trademark Office issued three patents covering processes and products manufactured using Solidia Technologies‘cement and carbon-curing technology. The patents extend the range of applications for Solidia’s processes to include hollow core, pervious and aerated concrete.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190516006022/en/

Global Quantum Secure Communication market analysis mainly introduces the changing market dynamics in terms of covering all details inside analysis and opinion, volume and value market share by players, by regions, by product type, by consumers and their price change details, cost/revenue structure. Additionally, the analysis of Global Quantum Secure Communication offers a detailed breakdown of key market growth drivers and limitation along with impact analysis of the same.

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WASHINGTON — If you’ve ever tried to swat a fly, you know that insects react to movement extremely quickly. A newly created biologically inspired compound eye is helping scientists understand how insects use their compound eyes to sense an object and its trajectory with such speed. The compound eye could also be used with a camera to create 3D location systems for robots, self-driving cars and unmanned aerial vehicles.

In The Optical Society (OSA) journal Optics Letters, researchers from Tianjin University in China report their new bio-inspired compound eye, which not only looks like that of an insect but also works like its natural counterpart. Compound eyes consist of hundreds to thousands of repeating units known as ommatidia that each act as a separate visual receptor.

“Imitating the vision system of insects has led us to believe that they might detect the trajectory of an object based on the light intensity coming from that object rather than using precise images like human vision,” said Le Song, a member of the research team. “This motion-detection method requires less information, allowing the insect to quickly react to a threat.”

An update on the development of a system that will land NASA Astronauts on the Moon as a part of our #Artemis program, the final four sites selected for our first asteroid sample return mission and our Parker Solar Probe spacecraft prepares for another close encounter with the Sun … a few of the stories to tell you about – This Week at NASA!

In what is being called an “unprecedented” discovery, a limestone sarcophagus containing the skeleton of a woman dating to the 7th century has been unearthed by archaeologists in Cahors, in southwestern France.

The discovery of the coffin, believed to be from the mysterious Merovingian era, was made as part of excavations carried out ahead of a redevelopment project by the archaeological unit of the Department of Lot, in cooperation with specialists from France’s National Institute of Preventive Archaeological Research.

Throughout the densely-populated country of Bangladesh, a lack of access to clean drinking water is responsible for a variety of debilitating and often-lethal infections. Soon, however, residents could filter virtually all harmful microbes out of their water, using paper derived from algae.

Researchers from the Austrian Academy of Sciences and the University of Vienna have experimentally demonstrated what was previously only a theoretical possibility. Together with quantum physicists from the University of Science and Technology of China, they have succeeded in teleporting complex high-dimensional quantum states. The research teams report this international first in the journal “Physical Review Letters”.

In their study, the researchers teleported the quantum state of one photon (light particle) to another distant one. Previously, only two-level states (“qubits”) had been transmitted, i.e., information with values “0” or “1”. However, the scientists succeeded in teleporting a three-level state, a so-called “qutrit”. In quantum physics, unlike in classical computer science, “0” and “1” are not an ‘either/or’ – both simultaneously, or anything in between, is also possible. The Austrian-Chinese team has now demonstrated this in practice with a third possibility “2”.

Novel experimental method.