genetics – Lifeboat News: The Blog https://lifeboat.com/blog Safeguarding Humanity Fri, 19 Apr 2024 15:31:29 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 Large genomic study finds tri-ancestral origins for Japanese population https://lifeboat.com/blog/2024/04/large-genomic-study-finds-tri-ancestral-origins-for-japanese-population https://lifeboat.com/blog/2024/04/large-genomic-study-finds-tri-ancestral-origins-for-japanese-population#respond Fri, 19 Apr 2024 15:31:29 +0000 https://lifeboat.com/blog/2024/04/large-genomic-study-finds-tri-ancestral-origins-for-japanese-population

A multi-institutional team of geneticists and genomic and genotyping specialists in Japan has sequenced the genomes of thousands of Japanese people from across the country, looking to settle the debate surrounding the ancestry of the Japanese people.

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How a Single Gene Could Become a Volume Knob for Pain https://lifeboat.com/blog/2024/04/how-a-single-gene-could-become-a-volume-knob-for-pain https://lifeboat.com/blog/2024/04/how-a-single-gene-could-become-a-volume-knob-for-pain#respond Fri, 19 Apr 2024 01:26:05 +0000 https://lifeboat.com/blog/2024/04/how-a-single-gene-could-become-a-volume-knob-for-pain

Harnessing rare genetic mutations could help end America’s opioid epidemic.

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Novel Schizophrenia Insights from Brain Organoids and Genes https://lifeboat.com/blog/2024/04/novel-schizophrenia-insights-from-brain-organoids-and-genes https://lifeboat.com/blog/2024/04/novel-schizophrenia-insights-from-brain-organoids-and-genes#respond Thu, 18 Apr 2024 19:34:00 +0000 https://lifeboat.com/blog/2024/04/novel-schizophrenia-insights-from-brain-organoids-and-genes

Although schizophrenia can be a very complex illness some new studies show that some major genetic factors could be the cause and then cured much easier through gene therapy.


Summary: Researchers leveraged cutting-edge technology to gain insights into schizophrenia’s neurodevelopmental origins. The researchers grew brain organoids from patients’ skin cells, finding persistent axonal disruptions in those with schizophrenia.

In another study, researchers zeroed in on a schizophrenia risk gene, CYFIP1, revealing its potential role in brain immune cells called microglia and their influence on synaptic pruning – a crucial process for brain health.

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Decoding the Mysteries of Life and the Cosmos: A Journey Through the Last Decade of Science https://lifeboat.com/blog/2024/04/decoding-the-mysteries-of-life-and-the-cosmos-a-journey-through-the-last-decade-of-science https://lifeboat.com/blog/2024/04/decoding-the-mysteries-of-life-and-the-cosmos-a-journey-through-the-last-decade-of-science#respond Wed, 17 Apr 2024 13:44:19 +0000 https://lifeboat.com/blog/2024/04/decoding-the-mysteries-of-life-and-the-cosmos-a-journey-through-the-last-decade-of-science

I found this on NewsBreak: Decoding the Mysteries of Life and the Cosmos: A Journey Through the Last Decade of Science.


By: Jason St Clair.

It’s worth reflecting on the scientific breakthroughs that have shaped our understanding of the universe and ourselves from 2010 to 2019. From the creation of synthetic life to the first glimpse of a black hole, these discoveries remind us of the indomitable human spirit and our unending quest for knowledge.

In 2010, scientists at the J. Craig Venter Institute played the role of cosmic composers, creating the first living organism with a completely synthetic genome. This milestone marked the first step in producing artificial life, a symphony of genetic notes designed in a computer, assembled in a lab, and brought to life in a donor cell. It was a testament to our growing mastery over the building blocks of life itself.

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Attempting To Slow The Epigenetic Pace Of Aging (13-Test Analysis) https://lifeboat.com/blog/2024/04/attempting-to-slow-the-epigenetic-pace-of-aging-13-test-analysis https://lifeboat.com/blog/2024/04/attempting-to-slow-the-epigenetic-pace-of-aging-13-test-analysis#respond Sun, 14 Apr 2024 13:23:48 +0000 https://lifeboat.com/blog/2024/04/attempting-to-slow-the-epigenetic-pace-of-aging-13-test-analysis

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhDDiscount Links: Epigenetic Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQ

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Newly Found Genetic Variant Defends Against Alzheimer’s Disease https://lifeboat.com/blog/2024/04/newly-found-genetic-variant-defends-against-alzheimers-disease https://lifeboat.com/blog/2024/04/newly-found-genetic-variant-defends-against-alzheimers-disease#respond Sat, 13 Apr 2024 15:42:24 +0000 https://lifeboat.com/blog/2024/04/newly-found-genetic-variant-defends-against-alzheimers-disease

Columbia neuroscientists have identified a genetic mutation that fends off Alzheimer’s in people at high risk and could lead to a new way to protect people from the disease.

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Large NIH Grant Supports CRISPR-based Gene Therapy Development for Brain Diseases https://lifeboat.com/blog/2024/04/large-nih-grant-supports-crispr-based-gene-therapy-development-for-brain-diseases https://lifeboat.com/blog/2024/04/large-nih-grant-supports-crispr-based-gene-therapy-development-for-brain-diseases#respond Sat, 13 Apr 2024 01:23:56 +0000 https://lifeboat.com/blog/2024/04/large-nih-grant-supports-crispr-based-gene-therapy-development-for-brain-diseases

If we can prove the concept of this technology in the two diseases we’re studying, we can then apply it to hundreds or thousands of diseases of the brain.

Yong-Hui Jiang, MD, PhD

Yes, please. Huntington disease hopefully.


The two-phase grant will support research into a novel CRISPR-based gene-editing technology and delivery platform for targeting neurogenetic diseases.

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Longer-Lived People Have Less Epigenetic Noise https://lifeboat.com/blog/2024/04/longer-lived-people-have-less-epigenetic-noise https://lifeboat.com/blog/2024/04/longer-lived-people-have-less-epigenetic-noise#respond Fri, 12 Apr 2024 15:22:51 +0000 https://lifeboat.com/blog/2024/04/longer-lived-people-have-less-epigenetic-noise

A team of researchers has reported in Aging Cell that longer-lived Chinese women have less epigenetic noise in crucial areas of the genome. Order and disorder We have previously reported that the accumulation of epigenetic noise appears […].

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Researchers find the “recipe” for growing new limbs https://lifeboat.com/blog/2024/04/researchers-find-the-recipe-for-growing-new-limbs https://lifeboat.com/blog/2024/04/researchers-find-the-recipe-for-growing-new-limbs#respond Fri, 12 Apr 2024 15:22:38 +0000 https://lifeboat.com/blog/2024/04/researchers-find-the-recipe-for-growing-new-limbs

For as long as superheroes have been imagined, there’s been a superhero who can regrow limbs. Other animals (like salamanders and sharks) do it, why couldn’t we? Scientists have also tackled this question because, obviously, humans don’t naturally regrow limbs. But before we move on to regrowing limbs ourselves, we need to understand how other species do it.

In a new study, researchers mapped the proteins that kick off limb creation in mice and chicks, finding that a cocktail of just three proteins performs the initial magic.

“People in the field have known a lot of the proteins critical for limb formation, but we found that there are proteins we missed,” said study co-first author ChangHee Lee, research fellow in genetics in the lab of Cliff Tabin at Harvard Medical School.

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New study finds potential targets at chromosome ends for degenerative disease prevention https://lifeboat.com/blog/2024/04/new-study-finds-potential-targets-at-chromosome-ends-for-degenerative-disease-prevention https://lifeboat.com/blog/2024/04/new-study-finds-potential-targets-at-chromosome-ends-for-degenerative-disease-prevention#respond Fri, 12 Apr 2024 03:23:16 +0000 https://lifeboat.com/blog/2024/04/new-study-finds-potential-targets-at-chromosome-ends-for-degenerative-disease-prevention

We depend on our cells being able to divide and multiply, whether it’s to replace sunburnt skin or replenish our blood supply and recover from injury. Chromosomes, which carry all of our genetic instructions, must be copied in a complete way during cell division. Telomeres, which cap the ends of chromosomes, play a critical role in this cell-renewal process—with a direct bearing on health and disease.

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