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How Gene Therapy and Algae Proteins Partially Restored a Blind Man’s Sight

The result is optogenetics, a mind-controlling technique that’s become one of neuroscience’s most popular tools. Here, scientists use genetic engineering to put different types of algae proteins into the brains of mice. They can then activate a neuron with an implanted fiber optic cable by pulsing certain wavelengths of light. These enhanced brain cells react as they would naturally, generating an electrical signal that’s passed down and interpreted by the mouse’s brain.

Sound familiar?

If an algae protein can artificially allow neurons in the brain to translate light into electrical information, why can’t it do the same for damaged eyes?

Aging Teeth and Radical Life Extension

I know that this is controversial in the longevity community, but there was overwhelming agreement among the dentists I talked with that mouthwash is excellent for preventing gingivitis (one study found that it was more effective than flossing) and reducing plaque.


Are you working to extend your healthspan and lifespan? Address the most common aging teeth problems with these dentist-approved tricks.

Lisa Gable — Chief Executive Officer — Food Allergy Research & Education (FARE)

Improving Quality Of Life & Health, For Hundreds Of Millions Globally, Suffering Food Allergies & Intolerances — Lisa Gable, Chief Executive Officer, Food Allergy Research & Education (FARE)


Lisa Gable is the Chief Executive Officer, of Food Allergy Research & Education (FARE — https://www.foodallergy.org), an organization with a mission to improve the quality of life and the health of 85 million Americans with food allergies and food intolerances, including 32 million of those are at risk for life-threatening anaphylaxis, and to provide them hope through the promise of new treatments. To date FARE has turned over $100 million in donor gifts into ground-breaking research and has provided a voice for the community, advocating on its behalf and offering hope for a better tomorrow.

Ms. Gable has served four U.S. presidents and two governors, counseled Fortune 500 CEOs, and represented global public-private partnerships and non-profits with an end goal of moving organizations to higher levels of performance.

As the former President of the Healthy Weight Commitment Foundation, Ms. Gable created and led a coalition of food and beverage industry corporations and public health and government agencies, resulting in the reduction of 6.4 trillion calories from the American diet.

Ms Gable was appointed the first female U.S. Commissioner General to the 2005 Aichi World EXPO, holding the personal rank of Ambassador, served as a U.S. Delegate to the United Nations Commission on the Status of Women, and served both in the Reagan White House and Defense Department, serving as an advisor to the Secretary of Defense and the Joint Chief of Staff.

Gottlieb says U.S. likely “much further in this epidemic than we’re picking up”

I believe since the weird localization of the virus in Japan that this sorta self evolving virus needs to have a counter like a self evolving vaccine but at the very least new variants can be made super fast with new technology in vaccine making.


Washington — Dr. Scott Gottlieb, former Food and Drug Administration commissioner, said Sunday he thinks the U.S. is further into the COVID-19 epidemic driven by the Delta variant than Centers for Disease Control and Prevention (CDC) models are picking up. He said that could mean “hopefully we’re going to turn a corner” in the next two to three weeks.

“We’re not doing a lot of testing. More of the testing that we are doing is antigen tests that are being done at home and not getting reported,” Gottlieb said. “So, I think we’re much further into this epidemic than we’re picking up and hopefully further through this epidemic.”

Drones could help save soldiers’ lives by delivering blood on demand

Getting blood to a wounded soldier could be the difference between life and death. A drone swarm is one way to make that happen in battle.


Blood is usually a finite quality on a battlefield. Battles can cause a number of injuries, from the minor to the critical. If a soldier can get the wound closed in time, they can staunch the loss, but keeping the patient alive may require an influx of new blood. As medics work to aid their comrades, they could receive help from an unusual source: delivery drones, bringing literal fresh blood to the battlefield.

A drone swarm capable of delivering blood was part of Autonomous Advance Force 4.0, an exercise by the United Kingdom’s armed forces in which Royal Marines Commandos trained with modern technology for future war. The July exercise took place in Cumbria and Dorset, with a release announced July 17.

The swarm consisted of six medium-heavy lift drones, Malloy Aeronautics TRV-150s. The TRV-150 can carry up to 140 lbs, at a range of up to 43 miles, with a maximum flight time of 36 minutes. Malloy drones got their start back in 2014 as a hoverbike concept, which was then proposed for the US military as a kind of ridden-drone scout. The US Army explored a large version of the drone as a “tactical resupply” vehicle in 2017. In TRV-150 form, the drone is an octocopter, with two rotors on each of four limbs.

TRIIM-X 2nd Phase Clinical Trial For Reversing Human Aging | Study Review

A summary of the sequel trial for a cocktail of drugs that originally turned back epigenetic clocks by 2.5 years. I do wonder what effect plasma filtering has on the thymus if any.


In this video we review the TRIIM study and look at the trial document for TRIIM-X, the extension study that Dr. Fahy is now conducting.

Timing — If you are familiar with the TRIIM Study please use the time links below to jump to TRIIM-X
0:12 : TRIIM Paper Review.
7:11 : TRIIM-X Trial Review.
08:59 : TRIIM vs TRIIM-X

Papers referred to in this video.
Reversal of epigenetic aging and immunosenescent trends in humans Sept 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826138/

Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial (TRIIM-X)

Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria

Original Article from The New England Journal of Medicine — Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria.


Dr. Moses, Mr. Metzger, and Ms. Liu contributed equally to this article.

A data sharing statement provided by the authors is available with the full text of this article at NEJM.org.

We thank the study participant “Bravo-1” for his dedication and commitment; the members of Karunesh Ganguly’s laboratory for help with the clinical study; Mark Chevillet, Emily Mugler, Ruben Sethi, and Stephanie Thacker for support and feedback; Nick Halper and Kian Torab for hardware technical support; Mariann Ward for clinical nursing support; Matthew Leonard, Heather Dawes, and Ilona Garner for feedback on an earlier version of the manuscript; Viv Her for administrative support; Kenneth Probst for illustrating an earlier version of Figure 1; Todd Dubnicoff for video editing; and the participant’s caregivers for logistic support.

Brain-Repair Discovery Could Lead to New Epilepsy Treatments

Using high-powered imaging, the researchers were able to see, for the first time, that immune cells called microglia were not just removing damaged material after experimental seizures but actually appeared to be healing damaged neurons.


Summary: Microglia do not only remove damaged materials following a seizure, they also appear to heal damaged neurons.

Source: University of Virginia

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.

Common seizure-preventing drugs do not work for approximately a third of epilepsy patients, so new and better treatments for such brain injuries are much needed. UVA’s discovery identifies a potential avenue, one inspired by the brain’s natural immune response.

Investigational Magnetic Device Shrinks Glioblastoma in First-in-World Human Test

Summary: A novel helmet that generates a noninvasive oscillating magnetic field was able to reduce tumor mass by 31% in a glioblastoma brain cancer patient.

Source: Houston Methodist.

Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating magnetic field that the patient wore on his head while administering the therapy in his own home. The 53-year-old patient died from an unrelated injury about a month into the treatment, but during that short time, 31% of the tumor mass disappeared. The autopsy of his brain confirmed the rapid response to the treatment.