John Davies – Lifeboat News: The Blog https://lifeboat.com/blog Safeguarding Humanity Tue, 05 Nov 2024 23:22:33 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.2 Bill Faloon on Age Reversal at RAADfest 2024 (Keynote Presentation) https://lifeboat.com/blog/2024/11/bill-faloon-on-age-reversal-at-raadfest-2024-keynote-presentation https://lifeboat.com/blog/2024/11/bill-faloon-on-age-reversal-at-raadfest-2024-keynote-presentation#respond Tue, 05 Nov 2024 23:22:33 +0000 https://lifeboat.com/blog/2024/11/bill-faloon-on-age-reversal-at-raadfest-2024-keynote-presentation

In his keynote presentation at RAADfest 2024, Bill Faloon discusses research updates about age-reversal research including IL-11 inhibition, young plasma transfer, epigenetic reprogramming, and other topics.

]]>
https://lifeboat.com/blog/2024/11/bill-faloon-on-age-reversal-at-raadfest-2024-keynote-presentation/feed 0
E5 treatment showing improved health‐span and lifespan in old Sprague Dawley rats https://lifeboat.com/blog/2024/09/e5-treatment-showing-improved-health%e2%80%90span-and-lifespan-in-old-sprague-dawley-rats Mon, 23 Sep 2024 08:23:40 +0000 https://lifeboat.com/blog/2024/09/e5-treatment-showing-improved-health%e2%80%90span-and-lifespan-in-old-sprague-dawley-rats

In the present investigation, the SD rats were separated into two groups old control group and the treatment group (n = 8). The treatment group received four injections of E5 every alternate day for 8 days, and eight injections every alternate day for 16 days. Body weight, grip strength, cytokines, and biochemical markers were measured for more than 400 days of the study. Clinical observation, necropsy, and histology were performed. The E5 treatment exhibited great potential by showing significantly improved grip strength, remarkably decreased pro-inflammatory markers of chronic inflammation and oxidative stress, as well as biomarkers for vital organs (BUN, SGPT, SGOT, and triglycerides), and increased anti-oxidant levels. Clinical examinations, necropsies, and histopathology revealed that the animals treated with the E5 had normal cellular structure and architecture. In conclusion, this unique ‘plasma-derived exosome’ treatment (E5) alone is adequate to improve the health-span and extend the lifespan of the old SD rats significantly.

]]>
Mehmood Khaan of Hevolution delivery a powerful speech on Longevity at RSS 2024 in Berlin https://lifeboat.com/blog/2024/05/mehmood-khaan-of-hevolution-delivery-a-powerful-speech-on-longevity-at-rss-2024-in-berlin Sun, 12 May 2024 12:22:31 +0000 https://lifeboat.com/blog/2024/05/mehmood-khaan-of-hevolution-delivery-a-powerful-speech-on-longevity-at-rss-2024-in-berlin

Mehmood Khaan opening the Rejuvenation Startup Summit with an outstanding speech on the state of longevity and the groundbreaking work that Hevolution is doing in funding scientists around the globe.

With the Rejuvenation Startup Summit in Berlin the Forever Healthy Foundation produced a great platform for founders and investors to meet and learn from and about eachother.

]]>
The fountain of youth is … a T cell? https://lifeboat.com/blog/2024/01/the-fountain-of-youth-is-a-t-cell Fri, 26 Jan 2024 00:27:50 +0000 https://lifeboat.com/blog/2024/01/the-fountain-of-youth-is-a-t-cell

“If we give it to aged mice, they rejuvenate. If we give it to young mice, they age slower. No other therapy right now can do this.”


The fountain of youth has eluded explorers for ages. It turns out the magic anti-aging elixir might have been inside us all along.

Cold Spring Harbor Laboratory (CSHL) Assistant Professor Corina Amor Vegas and colleagues have discovered that T cells can be reprogrammed to fight aging, so to speak. Given the right set of genetic modifications, these white blood cells can attack another group of cells known as senescent cells. These cells are thought to be responsible for many of the diseases we grapple with later in life.

Senescent cells are those that stop replicating. As we age, they build up in our bodies, resulting in harmful inflammation. While several drugs currently exist that can eliminate these cells, many must be taken repeatedly over time.

]]>