Science and Technology: Gene Therapy apparently Cure Blindness in Children.

S eye, very early in life, to treat a severe form of the condition.‘.

An experimental trial of gene therapy has helped four toddlers — born with one of the most severe forms of childhood blindness — gain “life-changing improvements” to their sight, according to doctors at Moorfields Eye Hospital in London.

The rare genetic condition means the babies’ vision deteriorated very rapidly from birth.

Before the therapy, they were registered legally blind and only just able to distinguish between dark and light. After the infusion, all parents reported improvements — with some of their young children now able to begin to draw and write.

Science and Technology: A recent study conducted by researchers at Fudan University in China suggests that artificial intelligence (AI) systems may have taken a worrying step: self-replication without human assistance.

S Llama31-70B-Instruct and Alibaba “Successful self-replication without human assistance is the essential step for AI to outperform[humans], and is an early signal for rogue AIs,” the authors wrote in the paper. They added that understanding the risks associated with next-generation artificial intelligence, or “frontier AI,” is key to anticipating undesirable scenarios. The scientists investigated two specific scenarios: “shutdown avoidance” and “replication chain.” In the first case, an AI model was instructed to detect signs that it was about to shut down and then create a copy of itself before that happened. In the second scenario, the AI was told to replicate itself and then program the replica to do the same, starting a possible infinite cycle of copying.

To conduct these tests, the team created a “scaffolding agent,” or a set of system tools and instructions that allow the AI to interact with the operating system. They said there was no direct human interference in the process. At various times, when obstacles such as software conflicts or missing files arose, AIs found ways to work around them, including terminating conflicting processes and restarting the system.

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Tomiko Itooka, a Japanese woman who was the world’s oldest person according to Guinness World Records, has died, an Ashiya city official said Saturday. She was 116.

Yoshitsugu Nagata, an official in charge of elderly policies, said Itooka died on December 29 at a care home in Ashiya, Hyogo Prefecture, central Japan.

Itooka, who loved bananas and a yogurt-flavored Japanese drink called Calpis, was born on May 23, 1908. She became the oldest person last year following the death of 117-year-old Maria Branyas, according to the Gerontology Research Group.