Dr. Prem PaisThe AP article Once-a-day heart combo pill shows promise in study said
A single daily pill that combines aspirin and four blood pressure and cholesterol medicines has passed its first big test, potentially offering a cheap, simple way to prevent both heart disease and stroke.
The experimental “polypill” proved as effective as nearly all of its components taken alone, with no greater side effects, a major study found. Taking it could cut a person’s risk of heart disease and stroke roughly in half, the study concludes.
This “one-size-fits-most” approach could make heart disease prevention much more common and effective, doctors say.
The study was led by Dr. Salim Yusuf of McMaster University in Hamilton, Ontario, and Dr. Prem Pais of St. John’s Medical College, Bangalore, India.
Prem Pais, MBBS, M.D. is
Head, Division of Clinical Trials, St. John’s Research Institute;
Dean, St. John’s Medical College; and
Professor of Medicine, St. John’s Medical College
Prem coauthored Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study, Telmisartan to Prevent Recurrent Stroke and Cardiovascular Events, Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke, Relationship of glucose and insulin levels to the risk of myocardial infarction: a case-control study, Effects of fondaparinux in patients with ST-segment elevation acute myocardial infarction not receiving reperfusion treatment, and Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data.
Prem earned his MBBS at St Johns Medical College, Bangalore in 1970 and his M.D. at Delhi University in 1974.
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